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COPD


Introduction




  • Chronic obstructive pulmonary disease (COPD) is a disease state characterized by chronic airflow obstruction.
  • Pulmonary function testing is central to its diagnosis

Evaluation of COPD


  • Airflow obstruction is determined by a reduced ratio of the forced expiratory volume in 1 s (FEV) to the forced vital capacity (FVC).
  • Patients suffering from COPD have reduced forced vital capacity.

Stage

FEV/FCV

Stage I

Greater than 80%

Stage II

50-80%

Stage III

30-50%

Stage IV

Less than 30%

Symptoms of COPD


Symptoms of COPD includes-


  • Dyspnea (Exacerbation)
  • Cough (Exacerbation)
  • Phlegm  production (Exacerbation)
  • Rhonchi
  • Other symptoms of COPD are wheezing, chest tightness, and tiredness.
  • People with advanced (very severe) COPD sometimes develop respiratory failure.

Risk factors of COPD




  • Cigarette smoking
  • Individuals with airway hyper responsiveness and certain occupational exposures
  • Biomass combustion with poor ventilation

Investigation of COPD


  • Patient who usually have smoked ≥20 pack-years of cigarettes.
  • Patients suffering from chronic bronchitis with the history of chronic productive cough for 3 months per year for the preceding 2 years.
  • Dyspnea, especially with exertion.
  • Patients find difficulty in exercise involving upper-body activity.
  • Weight loss and cachexia
  • Hypoxemia and hypercarbia may result in fluid retention
  • Morning headaches
  • Sleep disruption
  • Erythrocytosis
  • Cyanosis
  • Exacerbations

Physical Findings of COPD


  • The physical examination may be normal until COPD is fairly advanced.
  • As disease progresses, signs of hyperinflation may become more prominent.
  • Wheezing is occasionally observed
  • Persistently localized wheezing raises the possibility of lung cancer.
  • During COPD exacerbations, signs of respiratory distress may be prominent, including tachycardia, tachypnea, use of accessory muscles of respiration, and cyanosis.



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